The Buffaloes started the season with three wins: Colorado State (in the Rocky Mountain Showdown), at Washington State and back home against North Texas. The Colorado Buffaloes came into the game with a 7–4 record they were co-champions of the North Division (with Iowa State) and got into the championship game via head-to-head result. They finished the season with wins at home against Nebraska and at Baylor. Their next two games were both road games against ranked conference opponents they beat #20 Oklahoma State and #22 Texas A&M.
Oklahoma then beat Kansas State on the road then returned home for their homecoming game against Kansas. The Sooners then traveled to Dallas for the Red River Shootout against #5 Texas, which they won 12-0. They started the season with four home games, defeating Bowling Green, Houston, Oregon, and Texas Tech. The Oklahoma Sooners came into the game with a perfect 11–0 record and #2 in the nation. The #2 Oklahoma Sooners defeated the Colorado Buffaloes 42-3. The game determined the 2004 football champions of the Big 12 Conference. The 2004 Dr Pepper Big 12 Football Championship Game was played on Decemin Arrowhead Stadium in Kansas City, Missouri. $ – BCS representative as conference champion.
